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New UCB Data Presented at the Annual European Congress of Rheumatology

June 12, 2018

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New UCB Data Presented at the Annual European Congress of Rheumatology (EULAR 2018) Serves Key Patient Populations Including Ankylosing Spondylitis, Psoriatic Arthritis, and Women with Chronic Inflammatory Diseases

UCB, a global biopharmaceutical company focusing on immunology, neurology and bone treatment and research, will be presenting new data on CIMZIA® (certolizumab pegol) and key pipeline molecules bimekizumab and romosozumab at the Annual European Congress of Rheumatology (EULAR 2018), taking place in Amsterdam, June 13-16, 2018.

As a part of a late-breaking oral presentation, week 12 findings from the BE AGILE study will be presented for the first time, revealing the promising treatment effect of bimekizumab in patients living with ankylosing spondylitis (AS) and suggesting the potential breakthrough value of neutralizing IL-17F in addition to IL-17A. A separate presentation of long-term findings from RAPID-PsA on CIMZIA in psoriatic arthritis (PsA) will focus on the sustained achievement of stringent clinical outcomes, with a substantial proportion of patients achieving complete remission or very low disease activity.

An additional oral presentation will offer insight into the positive effect in building bone with one year of romosozumab.

“We are proud to present impressive findings on our pipeline molecules as well as the sustained value of CIMZIA in populations with specific treatment needs, such as women of childbearing age and patients with PsA and AS. The data that will be presented this week exemplify our mission to understand the needs of underserved patient populations, and connect them with scientific advancements that can provide real and immediate impact,” said Emmanuel Caeymaex, Head of Immunology and Executive Vice President, Immunology Patient Value Unit, UCB. “We are committed to serving as partners in care by understanding and supporting patients and rheumatologists, who are engaging especially challenging treatment situations, so we can bring the broadest possible value to patients in need.”

Additional presentations include survey findings from both patients and healthcare professionals (HCP) on specific challenges involved in the treatment of chronic inflammatory diseases in women of childbearing age. Findings from the patient survey, “Fears and Misconceptions of Women with Chronic Rheumatic Disease on Their Journey to Motherhood,” suggest that many women’s decisions to delay pregnancy or interrupt their treatment may be linked to the need for greater awareness of disease management options and earlier consultation with their HCPs. Also to be presented are findings from a SERMO survey of practicing HCPs, exploring the physician perspective on the challenges specific to treating women with chronic inflammatory diseases during family planning. Results from the largest published cohort of pregnant women exposed to an anti-TNF during pregnancy that will be presented at EULAR 2018 confirm that patients treated with certolizumab pegol did not experience increased risk of major congenital malformations compared to the general population nor an increased risk of fetal death.

Real world experiences of patients living with rheumatoid arthritis (RA) are explored in a poster presentation featuring analysis of data from the ArthritisPower Registry. Data suggest that rheumatologists tended to forego treatment changes, even when disease control goals were not met, with patients usually deferring to their HCPs. Other CIMZIA data featured at EULAR 2018 include data on ava, the auto-injection e-device, and the impact of the [email protected] patient support program.

In addition to 11 data presentations, UCB will be sponsoring two satellite symposia highlighting research and innovations in the treatment landscapes of osteoporosis and axial spondyloarthritis (axSpA). The data presented by UCB at EULAR 2018 showcase the company’s commitment to connecting scientific innovation and insights into real-world patient goals and unmet needs to make a lasting difference in the lives of patients.

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