GHP / August 2017 21 The Treatment of Resistant Hypertension g Resistant hypertension cannot be controlled with medical therapies. Patients experiencing resistant hypertension are at four times greater risk of cardiovascular events compared with hypertensive patients achieving blood pressure targets. (2) The American Heart Association (AHA) estimates that high blood pressure costs the $46 billion each year, including the cost of healthcare services, medications to treat high blood pressure, and lost productivity. More information is available at www. vasculardynamics.com (1) Kearney PM, et al. Global burden of hypertension: Analysis of worldwide data. Lancet. 2005;365(9455):217-23 (2) Pierdomenico SD, Lapenna D, Bucci A, et al. Cardiovascular outcome in treated hypertensive patients with responder, masked, false resistant, and true resistant hypertension. Am J Hypertens. 2005;18: 1422-8.